Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari

Marziehalsadat, Jazyeri Shooshtari (2018) Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari. Masters thesis, University of Malaya.

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      Abstract

      Cancer is one of the leading causes of death globally and chemotherapy being an effective approach for treatment has to be closely monitored and scheduled. In this work optimal control theory is used to schedule the administration of Temozolomide as a chemo drug. After obtaining the Hamiltonian function the cases of singular arcs are discussed. It is shown that the control of this treatment consists of both finite order and infinite order singular arcs. Finite order singular arcs in this work are of the third order and can be derived after deriving the switching function (

      Item Type: Thesis (Masters)
      Additional Information: Research Report (M.A) - Faculty of Engineering, University of Malaya, 2018.
      Uncontrolled Keywords: Optimal control theory; Switching function; Hamiltonian function
      Subjects: T Technology > T Technology (General)
      Divisions: Faculty of Engineering
      Depositing User: Mrs Rafidah Abu Othman
      Date Deposited: 19 Sep 2019 07:39
      Last Modified: 19 Sep 2019 07:39
      URI: http://studentsrepo.um.edu.my/id/eprint/9975

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