Johnathan Tan, Wei Lun (2018) Battery of life (BOL) assessment in critically ILL patients / Johnathan Tan Wei Lun. Masters thesis, University of Malaya.
Abstract
This was a prospective observational study conducted in University Malaya Medical Centre (UMMC) from November 2017 until May 2018. The objective of this study was to check the association between parameters of Battery of Life (BOL) with the primary outcome (Death/Functional decline) at 30 days. The study population were adult patients aged more than 16 years old referred to crash team UMMC during the period of time. Paediatric patients and pregnant women were excluded. A total of 313 patients were recruited and followed up daily up until 30 days or until discharge and their daily BOL score were recorded. The 6 parameters of BOL concerned with the delivery of oxygen and energy at the tissue level, namely airway, breathing, circulation, haemoglobin, microcirculation and glucose levels, with each parameter having 4 grades of severity (25%; 50%; 75%; 100%) were determined. The daily BOL score is taken as the lowest of all these 6 parameters. The patients would then be followed up at 30 days to determine their primary outcome (death, functional decline, no functional decline). It was concluded that the day 1 BOL score does affect the primary outcome of patient at 30 day. Those scoring 25% had a higher relative risk of mortality of 1.54 times (p<0.001) and a higher relative risk of functional decline/mortality of 1.45 times (P<0.001) at 30 days. Minimum BOL also does affect the outcome of patient at 30 day with those scoring 25% had a higher relative risk of mortality 5.04 times (p<0.005) and a higher relative risk of functional decline/mortality of 2.71 times (p<0.005).
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